Time to “revise” race coefficient in GFR estimation

By Merih Tesfazghi

October 27th, 2020

Race categorization is a controversial topic. One famous example that partially illustrates this complex issue is the race of President Barack Obama. His parents are biracial, a white mother from Kansas and a black father from Kenya. While he grew up feeling completely at home in neither race, he now officially identifies himself as African American.

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Mark Brown
Africa Kicks Out Wild Polio

By Roa Harb

August 31, 2020

On August 25, 2020, Africa was declared free of wild poliovirus – a milestone in a journey that was launched in 1996 with the late South African president Nelson Mandela’s call to “kick polio out of Africa.” This public health achievement is fantastic news in these troubled times of the Covid-19 pandemic.

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Mark Brown
Why is it so hard to make a test for Coronavirus?

By Sarah Riley

May 3, 2020

The novel coronavirus outbreak has posed a challenge to diagnostic laboratory medicine, and that is to develop and validate testing for this new pathogen from scratch. There are many time-consuming steps involved in developing a method to ensure that the results are always accurate and meaningful. Supply and demand of reagents and testing consumables confound the situation.

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Mark Brown
The COVID-19 pandemic and the role of clinical laboratories

By Merih Tesfazghi

March 20, 2020

The coronavirus (COVID-19) disease is now a pandemic. The virus is highly contagious and has already infected and killed thousands of individuals across the globe. Unless contained and controlled swiftly, millions could die in a matter of a few months. Clinical laboratories play a crucial role in controlling the pandemic by facilitating early detection through widespread testing.

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Mark Brown
Beyond HIV and the other usual suspects

By Tim Amukele

March 9, 2020

Testing needs in poor countries are not just restricted to HIV, TB, malaria, and other usual suspects. The tests and services that are available in the West are needed just as urgently in low-resourced countries (LRC). If we choose to help, we must help in a way that honors this need for broad testing.

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Mark Brown
Prion Diseases: Rare but Terminal

By Merih Tesfazghi

February 25, 2020

Prion diseases are a group of rare, infectious, neurodegenerative disorders. The most common variant in humans is sporadic Creutzfeldt-Jakob disease (sCJD). The annual incidence of sCJD is 1 to 2 cases per million worldwide, and about 360 cases are reported annually in the United States. The median age of disease onset is 63 years, with a dismal survival rate of 4 to 6 months after symptom manifestation.

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Mark Brown
One World, One Health

By Sarah Riley

February 5, 2020

One Health is the idea that the health of people is connected to the health of animals and the environment. There is probably a place for laboratorians in One Health initiatives. One Health is something we should all consider when we think of Global Health.

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Mark Brown
Two Decades of Improving HbA1c Measurement for the Diagnosis of Diabetes

By Roa Harb

January 23, 2020

HbA1c has long been used to monitor glycemic control in patients previously diagnosed with diabetes. Since its foundation in 1996, NGSP has been critical in the improvement of HbA1c measurement accuracy and precision. This has allowed influential clinical organizations and regulatory bodies to recommend the use of HbA1c for the initial diagnosis of diabetes. Despite significant reductions in variability, there is room for improvement as performance limits continue to tighten.

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Mark Brown
Vertical, or horizontal, that is the question.

By Emily Glynn

January 10, 2020

There is perennial debate in global health over the merits of vertical vs. horizontal programs. As someone who is interested in building  high-quality, sustainable pathology and laboratory capacity, I have always been one of those vertical program skeptics.  

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Mark Brown
Saying Sorry: When an email is not enough

By Tim Amukele

December 24, 2019

In Pathology and Laboratory Medicine (PALM) we often work behind the scenes and for many of us this suits our personalities. However, there are times when we need to fight the urge to remain hidden or use email, and pursue a face-to-face interaction.

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Mark Brown
An Unexpected Burden

By Sarah Riley

November 7, 2019

A recent study from the Data and Demographics Committee of the World Federation of Hemophilia found that the prevalence of hemophilia is 3 times more prevalent than previously believed. In order to better understand the true prevalence of hemophilia, more information from middle and low income countries is needed.

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Mark Brown
The Birth and Demise of Ebola?

By Merih Tesfazghi

September 12, 2019

Is Ebola Virus Disease curable? Not yet. However, a multi-drug study for the treatment of EVD launched in November 2018 just a few months after Ebola outbreak in DRC shows promising efficacy.

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Mark Brown
We are the champions my friend

By Tim Amukele

July 31, 2019

I am reading ‘Bad Blood’, the book about Theranos: one of the biggest frauds that was ever foisted on the financial community and the world.

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